The Th17/Treg cell ratios in the MLN and LPL in the DSS+LiPg group and DSS+DePg group were significantly higher than those in the control group (Fig. 1n), indicating that the aggravation of colitis by gavage with Pg was well reflected by the Th17/Treg cell imbalance. The gene discussed is JUP; the disease is colitis.