A notable example is eIF4G1, which has been linked to both PD.105 and Lewy body dementia.106 eIF4G1 is a translation initiation factor that facilitates the recruitment of ribosomes and tRNAs to the 5’ cap structure of mRNA by acting as a scaffold in the eIF4F translation initiation complex.107 Additionally, studies have shown the relevance of tRNA enzymes in neurological disorders. Here, EIF4G1 is linked to nervous system disorder.