For example, myxoid liposarcoma can detect DDIT3 gene translocation by fluorescence in situ hybridization technique, while PDGFB is negative; (4) DFSP with muscular/myofibroblastic differentiation: Eosinophilic muscular nodules or bundles can provide certain hints for diagnosing this subtype; (5) Atrophic or plaque-type DFSP: Generally presents as skin atrophy, loose skin, or plaques, and the tumor is located in the superficial dermis, making it easy to confuse with dermatofibroma or fibrosis. Here, PDGFB is linked to skin atrophy.