DES and neoplasm: Nuclear fission is easy to see (Figs. 1, 2, 3, 4, 5).Immunohistochemical results show that the tumor cells diffusely express Nestin, a-SMA, SDHB, a small amount of CD34, and CD117, DOG-1, Calponin, h-Caldesmon, Desmin, S-100 and pan-cytokeratin (CKpan) are all negative.