To explore the changes in the number of blood cells in the peripheral blood after alterations in the gut microbiota and intestinal metabolites, we measured the levels of white blood cells, red blood cells, hemoglobin, platelets, neutrophils, lymphocytes, monocytes, eosinophils, basophils and albumin in the peripheral blood of 30 ESCC patients and analyzed them by single factor variance (Schedule S2). Here, ALB is linked to esophageal squamous cell carcinoma.