Gene expression analyses revealed significant convergence in canonical pathways (cell cycle, lysosome, and mTORC1) as well as less established pathways such as Myc, E2F, and inflammation (IFN-γ response, IL-6/JAK/STAT3, systemic lupus erythematosus, TLR signaling, immunoglobulin-mediated phagocytosis, NK cell–mediated cytotoxicity, and allograft rejection). This evidence concerns the gene STAT3 and systemic lupus erythematosus.