Additionally, we conducted a correlation analysis between recurrently mutated genes in MDS and ONECUT3 levels (Supplemental Table 5) and noted a correlation between high expression levels of ONECUT3 and mutant PHF6 (P = 0.029), WT IDH2 (P = 0.018), and WT KMT2D (P = 0.033). Here, KMT2D is linked to myelodysplastic syndrome.