CancerSEA single-cell sequencing data were also used to assess correlative relationships between PSME2 expression and 14 cancer functional states, revealing positive associations between PSME2 and the cell cycle, DNA repair, and DNA damage in non-small cell lung cancer (Figure S14B, Table S7), highlighting these as possible processes through which PSME2 shapes oncogenic progression. The gene discussed is PSME2; the disease is non-small cell lung carcinoma.