The relative PSME2 expression levels across different cell lines, obtained from CCLE data, are presented in Figure S1B. Data from the UALCAN database revealed protein-level PSME2 upregulation in COAD, OV, clear cell renal cell carcinoma, UCEC, LUAD, HNSC, and GBM, whereas the downregulation of this protein was evident in LIHC (Figure 2C). The gene discussed is PSME2; the disease is clear cell renal carcinoma.