HDAC6 and Central apnea: The finding that post-hypoxia (i.e., post-apnea) breathing in humans is associated with severe glottal closures (Dempsey et al., 2010; Strohl et al., 2012), raises the possibility that decreased expression of HDAC6 may contribute to obstruction of the upper airway in patients with obstructive apneas, and perhaps the expression of central apneas.