Furthermore, chemical peels, trichloroacetic acid, derma rollers, microneedling, and fractional CO2 lasers are a few of the numerous scar treatments available [29,30]. Oral contraceptives primarily function to prevent pregnancy in non-invasive methods, but they have been found useful in controlling acne in premenopausal women as they suppress the levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which are the endocrine factors for the development of acne [31]. Here, PLOD1 is linked to acne.