CXCL1, CXCL2, and CXCL5 secretion from tumour cells is elevated in the KPC (LSL-KrasG12D/+; LSL-Trp53R172H/+; Pdx1-Cre) mouse model, in comparison to the normal pancreas (186). The gene discussed is CXCL2; the disease is neoplasm.