BCAS2 and influenza: In predictor selection, DE analysis between high and low responders to influenza vaccine revealed that at days 1–3 post-vaccination, there were few DEGs but relatively more DFGs compared with baseline, among which BCAS2 (P = 7.042 × 10-3) and USH2A (P = 3.959 × 10-2) represented both top DEGs and DFGs downregulated in high responders.