Colocalization analysis supports a link between MS4A6A and AD (H4 = 0.987), female-specific HBMD with AD, and phenotypes with MS4A6A gene expression (Fig. 5d; AD versus female HBMD H4 = 0.998, MS4A6A gene expression versus female HBMD H4 = 0.997). This evidence concerns the gene MS4A6A and Alzheimer disease.