Actual arm equivalence was confirmed across samples through multiple other experiments, assessing multiple parameters like tumor content (Supplementary Fig. 4A), immune content (Supplementary Fig. 4A), percentage of proliferating tumor cells (Ki67 + ) (Supplementary Fig. 4A), explant viability (Supplementary Fig. 4B), gene expression using mRNA counts (Supplementary Fig. 4C), and proportions of various immune cells (Supplementary Fig. 4D). This evidence concerns the gene MKI67 and neoplasm.