We found that, compared with patients in the low-SGOL1-expression group, patients in the high-SGOL1-expression group presented significantly greater proportions of Th2 cells, T helper cells, Th1 cells, T cells, Tcm cells, macrophages, and Tregs (P < 0.05) and lower proportions of pDCs, Th17 cells, and NK cells (P < 0.05) (Fig. 5B); these changes in the proportions of infiltrating Th1 cells, Th2 cells, T cells, macrophages, Tregs and NK cells had great impacts on the tumor microenvironment and clinical prognosis of ccRCC patients [47, 48]. This evidence concerns the gene SGO1 and neoplasm.