GSEA was performed to assess the potential biological effect of SGOL1 on ccRCC and the signaling pathways through which SGOL1 exerts its effects, and the results suggested that the “hallmark epithelial–mesenchymal transition” (EMT) was enriched in patients with relatively high SGOL1 expression (Fig. 10B). Here, SGO1 is linked to nonpapillary renal cell carcinoma.