PPARG and breast carcinoma: Studies specifically in breast cancer have revealed the significant role of ligand-bound PPARγ in inhibiting the growth, metastasis, and invasion of breast cancer cells, impacting cell cycle regulation, and influencing both endogenous and exogenous apoptosis across various breast cancer subtypes, including ER + /PR + , ER-/PR-, HER + , and triple-negative breast cancer cells [143].