The Kaplan–Meier survival curve from the R2 database (https://hgserver1.amc.nl/cgi-bin/r2/main.cgi) indicate a lower expected overall survival rate for individuals with high ANP32B expression in acute myeloid leukemia (AML) compared to those with low ANP32B expression (Fig. 1E). The gene discussed is ANP32B; the disease is acute myeloid leukemia.