The results consistently supported the correlation between PCSK9 and HF in patients with CHD (PPH4: 99.998%), as well as between PCSK9 and HF in patients receiving antihypertensive medication (PPH4: 98.864%) (Table 1) Additionally, we observed a robust colocalization evidence for SWAP70 and HF in patients receiving antihypertensive medication (81.718%). This evidence concerns the gene PCSK9 and hydrops fetalis.