IFNG and skin basal cell carcinoma: Local administration of interferons has been used sporadically for the treatment of BCC8, 9, 10, 11, 12 but most recent clinical guidelines do not recommend this type of therapy.3, 4 This study evaluated the effect of perilesional administration of HeberFERON (a combination of alpha-2b and gamma interferons) in 195 patients with high-risk facial BCC not suitable for surgical treatment.