Hypoxia induction mediated by hypoxia-inducible factor 2α (HIF-2α) increases the epithelial-mesenchymal transition (EMT) events and NEAT1 expressions in NSCLC under hypoxic condition via regulating miR-101-3p/SOX9/Wnt/β-catenin signal pathway, promoting the progression of NSCLC [15]. The gene discussed is EPAS1; the disease is non-small cell lung carcinoma.