Secondly, there are numerous subtypes of TTN proteins that undergo selective cleavage to produce various skeletal and myocardial subtypes, including N2B, N2BA, and NOVEX-3 [9, 12] and are regulated by RNA binding motif protein (RBM) genes, which are associated with approximately 2% of DCM [13, 14]. Here, TTN is linked to familial dilated cardiomyopathy.