SLCO1B3 and metabolic dysfunction-associated steatohepatitis: BSEP, NTCP, and OATP1B1, OATP1B3 zonal abundance patterns in NDL biopsies were consistent with previous studies indicating high pericentral OATP1B3 abundance, less preferential pericentral OATP1B1 abundance, and nonpreferential zonal distribution of BSEP and also NTCP (Figure 1).22,31,32 In our NASH cohort, periportal increases and pericentral decreases in BSEP abundance were observed.