BSEP, NTCP, OATP1B1, and OATP1B3 are all glycosylated proteins with increased levels of their respective unglycosylated forms in NASH.44 However, the membrane localization of these proteins was differentially impacted across zones by NAFLD in our study suggesting that additional mechanisms are involved. This evidence concerns the gene SLCO1B1 and metabolic dysfunction-associated steatohepatitis.