ABCB11 and metabolic dysfunction-associated steatotic liver disease: Our finding of decreased pericentral BSEP abundance was corroborated by nonquantitative immunohistochemistry data that showed reduced BSEP abundance in regions with pronounced steatosis.17 It is reasonable to assume that these unspecified areas are located in the pericentral region because adult NAFLD is typically initiated through pericentral steatosis and inflammation.