The functional role of RECQL4 in HCC was investigated by comparing its expression in normal human liver cell lines (WRL‐68 and L02) and HCC cell lines (MHCC97H, Hep3B, Huh7, MHCC97L, HCCLM3, and HepG2) using qPCR and western blotting (WB). Here, RECQL4 is linked to hepatocellular carcinoma.