Decreased levels of CD8+ T cells (CD45+/CD3+/CD8+ cells) and antigen‐specific DCs (CD45+/CD11c+/SIINFEKL+ cells) in tumors/tumor‐draining lymph nodes (TDLN) in mice with subcutaneous graft HCC tumor carrying RECQL4 following irradiation‐induced DNA damage (Figure4A–D). This evidence concerns the gene CD8A and hepatocellular carcinoma.