Furthermore, GD2-CARrejTs with higher proportion of stem cell memory T cells (Fig. 2E), produced perforin, IFNγ, TNF, IL2, IL4, and IL10 at higher levels than did GD2-CARTs, leading to an advantage in GD2-CARrejTs against SCLC. The gene discussed is IL4; the disease is small cell lung carcinoma.