Recently, the neurohormone oxytocin, which is produced mainly in the PVN and acts as a neurotransmitter in the CNS, has been reported as a neuroprotective agent in ischemic injury and significantly reduces infarct in the cortex and striatum with its anti‐inflammatory and antioxidant properties,54, 55 suggest the prospective positive effects of oxytocin on the outcomes of stroke. Here, OXT is linked to stroke disorder.