EGF and Nasal polyposis: Given that the biochemical composition of nasal secretions quite faithfully reflects the inflammatory status of the nasal mucosa, examination of these parameters could show the state of the mucosal membrane during the healing process of mucosal wounds after FESS for nasal polyposis.11 As a key mediator in wound healing, epidermal growth factor is an effective mitogenic agent in epithelial cells, fibroblasts and vascular endothelial cells.