The effects of resveratrol were corroborated using in vitro and in vivo models where it was reported that resveratrol treatment of Hela cells, lymphoblasts, fibroblasts from FRDA patients, and brain tissues from YG8R FRDA mouse models lead to a significant expression of frataxin (Li et al., 2013; Georges et al., 2019). This evidence concerns the gene FXN and Friedreich ataxia.