Vascular endothelial growth factor (VEGF), matrix metalloproteinase 9 (MMP9), epidermal growth factor receptor (EGFR), and platelet-derived growth factor receptor, genes related to angiogenesis, are overexpressed in glioblastoma and presented on Glioblastoma-EVs surface [64]. This evidence concerns the gene MMP9 and glioblastoma.