A recent study developed in Tenerife (Spain) (8), found that most of the subjects (83.34%) with allergic rhinitis displayed a specific IgE response to more than eight mite HDM molecules, in contrast to patients with asthma (66.66%) or atopic dermatitis (66.66%), who showed a polysensitization profile to eight or more individual HDM allergens. Here, IGHE is linked to atopic eczema.