In Patient‐derived xenografts (PDXs), people found a link between IDC‐P and BRCA2 variant. PDXs from tumors with BRCA2 mutations had more IDC‐P cases than those with sporadic PCa. BRCA2 carriers with IDC‐P had worse survival rates compared to those without IDC‐P. This evidence concerns the gene BRCA2 and posterior cortical atrophy.