Besides MMP‐2, MMP‐3, and MMP‐9, other MMPs such as MMP‐1, MMP‐7, MMP‐8, and MMP‐12 have also been implicated in cerebral ischemia–reperfusion injury, although their specific roles and mechanisms are still being investigated.46, 47. This evidence concerns the gene MMP3 and Cerebral ischemia.