To confirm whether the interaction between YBX1 and hsa_circ_0007990 contributes to BC progression, we successfully transfected the pcDNA3.1-YBX1 plasmid into the MCF-7 cell line (Fig. 7A) and then performed rescue experiments in hsa_circ_0007990-knockdown cells. The gene discussed is YBX1; the disease is breast cancer.