In patients with MG, the expression of PI3KCA, AKT-1, mTORC1, HIF-1α, GLUT1, HK, PFK, and PK increased significantly in Th1, Th17, and CD4+ CD25− cells, and the expression of AKT-1, HIF-1α, GLUT1, PK, and CPT1A increased significantly in CD4+ CD25+ Tregs. This evidence concerns the gene HIF1A and myasthenia gravis.