CD8A and myasthenia gravis: In summary, these studies provide strong evidence of the critical role of CD8+ T cells in the pathogenesis of patients with MG with or without treatment, including patients with MG with or without other diseases, with in situ CD8+ T cells in the heart and skeletal muscle and CD8+ T cells in the CSF, as well as those undergoing different treatments, such as Tx and immunosuppressive therapy.