In addition, GPX4 was highly expressed in AML cells with t(8;21) carrying the AML1-ETO fusion gene, t(11q23) bearing MLL rearrangements, and inv(16) bearing CBFβ-MYH11 but not those with t(15;17) carrying PML-RARα (Fig. 1B). The gene discussed is RUNX1; the disease is acute myeloid leukemia.