Herein, the current study tried 1) to assess the predictive value of AOPP, IL-6, and GDF15 in relation to arteriosclerosis in patients with OSA; and 2) to examine the incremental value of AOPP, IL-6, and GDF15 in identifying arteriosclerosis in patients with OSA. The gene discussed is IL6; the disease is arteriosclerosis disorder.