Patients with SVZ + assigned tumors showed larger contrast-enhancing tumor volume (median 51.8 vs. 5.5 cm3) and a higher fraction of Karnofsky performance status (KPS) < 80% (n = 7, 24.1% vs n = 3, 12.0%), MGMT promoter methylation was less common (n = 9, 31.0% vs. n = 13, 52.0%). Here, MGMT is linked to neoplasm.