Age, gender, clinical features (heart rate, SBP, DBP, and BMI), vascular risk factors (hypertension, hypercholesterolemia, and diabetes mellitus), smoking and drinking history, RNF213 p.R4810K mutation status, and clinical type showed no statistically significant differences between the two groups (P > 0.05). The gene discussed is RNF213; the disease is Hypertension.