VEGFA and collecting duct carcinoma: Two patients initially diagnosed with CDC received chemotherapy but had the worst outcomes, VEGF was the most common treatment (Total, n = 9; Sorafenib, n = 1; Pazopanib, n = 2; Sunitinib, n = 3; Axitinib, n = 3), and showed the objective response rate (ORR) (22.2%) and DCR (55.5%).