Of those proteins, 11 proteins were identified and may be involved in brain disease, among these, five proteins (parvalbumin alpha, superoxide dismutase, S‐adenosyl‐l‐homocysteine hydrolase, 3‐mercaptopyruvate sulfurtransferase, and cathepsin S) are particularly related to neuroinflammation and cerebral ischemia. The gene discussed is CTSS; the disease is brain disorder.