The phenotype associations early neurodevelopmental disorders of gait abnormalities including such as Charcot‐Marie‐Tooth disease (CMT) gait abnormalities, Congenital cataracts, facial dysmorphism, and neuropathy (CCFDN), Bryant‐Li‐Bhoj neurodevelopmental syndrome‐1 (BRYLIB1) neurodevelopmental delay, agenesis of corpus callosum related peripheral neuropathy, pulmonary atresia, global developmental disorder including (Basilicata‐Akhtar) Syndrome, and neurodegenerative disorder Amyotrophic lateral sclerosis (ALS) (Figure 3b). This evidence concerns the gene H3-3A and Developmental cataract.