Remarkably, data from a new conditional P2X4 internalization‐defective knock‐in mouse, namely P2X4mCherryIN, which displays an increase in the number of P2X4 receptors at the surface of targeted cells, further supports the relation between neuronal P2X4 and anxiety‐like behavior as well as in memory.153. Here, P2RX4 is linked to Anxiety.