It has been demonstrated that supine exercise induces HGF production in patients with acute myocardial infarction.S44 For aortic valve stenosis patients and healthy persons, one‐hour peak bicycle exercise increased the blood levels of HGF.S45 The HGF protein was increased in the serum of humans at 4 h after muscle 300 lengthening contractions,S46 suggesting that HGF is an exercise‐induced cytokine. This evidence concerns the gene HGF and stricture.