It alters the sterol profile and blocks ergosterol biosynthesis.Moreover, AITC produces ROS in both planktonic and biofilm cells and arrests cells at the G2/M pre-apoptic phase.The AITC alters the expression of genes involved in the signal transduction pathway which inhibits germ tube formation by downregulating PDE2, CEK1, and TEC1 and upregulating TUP1, MIG1, and NRG1 genes.Toxicity assay has revealed that AITC can be used as an alternate therapeuticoption to treat candidiasis as it is non-toxic to human RBCs. Here, VPS4B is linked to Candidiasis, Invasive.