Although we need to carefully follow this case over time before making a conclusion on the possible causal link with vaccination, it is interesting to note that an increase in the detection of Hu-Abs (along with GFAP-Abs) was observed at the Barcelona Referral Center by comparing the pre–COVID-19 (2017–2019) and COVID-19 (2020–2021) periods, while the authors did not detect a substantial increase of encephalitis mediated by Abs against neural-surface antigens (46). Here, GFAP is linked to encephalitis.