SMARCA4 and neoplasm: BRG1 plays roles in carcinogenesis and tumor progression (Masliah-Planchon et al., 2015; Halliday et al., 2009), and BRG1 deficiency is associated with highly aggressive behavior and poor survival (Bell et al., 2016; Liang et al., 2023; Reisman et al., 2003).