Similarly, in hepatocellular carcinoma (HCC), p300 has been implicated in the significant reprogramming of super‐enhancers, leading to the upregulation of critical oncogenes, including MYC, MYCN, and CCND1, and fostering cancer cell proliferation both in vitro and in vivo.113. The gene discussed is MYC; the disease is hepatocellular carcinoma.