Sixty-seven variants were identified in 53 epilepsy-associated genes, and the most frequently mutated genes were PRRT2 (four families), TPP1 (three families), STXBP1 (three families), SCN1A (two families), ALG11 (two families), MECP2 (two families), CLN6 (two families), CACNA1A (two families), and KCNT1 (two families). The gene discussed is CLN6; the disease is epilepsy.