MKI67 and neoplasm: After 14 days of treatment, the tumour burden in the iFSP1 group was lower than that in the DMSO group; of note, the tumour burden was significantly lower in the combination group than in any single group (Fig. 7C, D), a finding that was also supported by the Ki-67 staining of the tumour sections in each group (Fig. 7E, F).