CEACAM5 and hepatocellular carcinoma: Some TSGs, such as epidermal growth factor receptor (EGFR), carcinoembryonic antigen (CEA), and prostate-specific membrane antigen (PSM), are utilized as biomarker to assist diagnosis and prognosis of various types of tumors whose cells express these TSGs [12], whilst HCC has no molecular markers that have been incorporated into clinical management [13].