Using the murine anti-CA125 antibody 18C6 as a positive control, we found that h4H11 H1L1, H1L2, and H2L1 antibodies significantly inhibited migration of OVCAR3, OVCA-433 and CAOV3 cells compared to untreated control tumor cells (p < 0.005; * compared to OVCAR3 control, ** compared to OVCAR-433 control, *** compared to CAOV3 control, n.s: not significant). The gene discussed is MUC16; the disease is neoplasm.