According to the analysis of the database, 6 hub DEGs (ACADM, ALDH7A1, FABP5, STX3, ACAT1, and HACD4) were highly expressed in PCOS GCs, and 2 hub DEGs (PTGDS and OXER1) were highly expressed in normal GCs (Fig. 1E). The gene discussed is ACAT1; the disease is polycystic ovary syndrome.